A new dihydroagarofuran sesquiterpene polyester, fokienagarofuran J (1), has been isolated from the roots of Microtropis fokienensis, together with six known compounds, 2,6-dimethoxy-p-benzoquinone (2), β-sitostenone (3), 6β-hydroxystigmast-4-en-3-one (4), celahin C (5), salasol A (6), and fokienagarofuran D (7). The structure of the new compound 1 was determined through spectroscopic and MS analyses. Among the isolates, fokienagarofuran J (1) and fokienagarofuran D (7) showed potent inhibition with IC50 values of 1.05 and 0.89 μg/mL, respectively, against the DLD-1 cell line. In addition, compounds 1 and 7 exhibited cytotoxicities, with IC50 values of 0.26 and 0.15 μg/mL, respectively, against IMR-32 cell line.

中文翻译：

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一种新的二氢琼脂呋喃倍半萜烯和福建小竹的细胞毒性成分

一种新的二氢琼脂呋喃倍半萜烯聚酯 fokienagarofuran J (1)，与六种已知化合物 2,6-二甲氧基-对苯醌 (2)、β-谷酮 (3)、6β- hydroxystigmast-4-en-3-one (4)、celahin C (5)、salasol A (6) 和 fokienagarofuran D (7)。通过光谱和质谱分析确定了新化合物 1 的结构。在分离株中，佛克林呋喃 J (1) 和佛基那呋喃 D (7) 对 DLD-1 细胞系显示出有效的抑制作用，IC50 值分别为 1.05 和 0.89 μg/mL。此外，化合物 1 和 7 表现出细胞毒性，对 IMR-32 细胞系的 IC50 值分别为 0.26 和 0.15 μg/mL。