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Design of coils for lateralized TMS on mice.
Journal of Neural Engineering ( IF 3.7 ) Pub Date : 2020-06-01 , DOI: 10.1088/1741-2552/ab89fe
Clemente Cobos Sánchez 1 , José Joaquín Jurado García , Miguel Ruiz Cabello , Mario Fernández Pantoja
Affiliation  

Objective. Translational studies on animals play a vital role in the advancement of transcranial magnetic stimulation (TMS) as clinical technique. Nonetheless the relevance of these procedures is frequently limited by the lack of TMS systems specifically designed for small animals capable of producing comparable stimulation conditions to those found in human TMS. In this work, we propose to take advantage of the versatility of recently introduced TMS coil design methods to produce optimal rodent-specific TMS stimulators. Approach. A stream function inverse boundary element method (IBEM) has been used for producing three small sized mice-specific TMS coils of different geometries. They have been created for unilateral hemispheric stimulation of the rodent brain, and several constraints have been considered in the design process to satisfy essential performance requirements, such as minimum stored magnetic energy, minimum power dissipation, optimised maximum current...

中文翻译:

小鼠侧向TMS线圈的设计。

目的。动物的转化研究在经颅磁刺激(TMS)作为临床技术的发展中起着至关重要的作用。然而,这些程序的相关性常常由于缺乏专门为能够产生与人类TMS所产生的刺激条件相当的刺激条件的小型动物而设计的TMS系统而受到限制。在这项工作中,我们建议利用最近引入的TMS线圈设计方法的多功能性来生产最佳的啮齿动物特异性TMS刺激器。方法。流函数逆边界元素方法(IBEM)已用于生产三种不同几何形状的小型小鼠专用TMS线圈。它们的创建是为了对啮齿动物的大脑进行单侧半球刺激,
更新日期:2020-06-01
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