Rigid and topologically constrained ethylene cross-bridged tetraazamacrocycles have been increasingly utilised for thirty years as they form remarkably stable transition metal complexes for catalysis, biomedical imaging, and inorganic drug molecule applications. Extending these benefits to pentaazamacrocycles has been achieved and a first transition metal complex prepared and structurally characterized.

中文翻译：

---

乙烯交叉桥联五氮杂大环及其Cu2 +配合物：受约束的配体拓扑和出色的动力学稳定性。

刚性和受拓扑约束的乙烯交桥四氮杂大环化合物由于在催化，生物医学成像和无机药物分子应用中形成了非常稳定的过渡金属配合物，因此已经越来越多地使用了三十年。已经实现了将这些益处扩展到五氮杂大环化合物，并且制备了第一过渡金属配合物并对其进行了结构表征。