Aedes aegypti (L.) is the primary vector of Zika, dengue, yellow fever, and chikungunya viruses. Insecticides used in mosquito control can help prevent the spread of vector-borne diseases. However, it is essential to determine insecticide resistance (IR) status before control measures are undertaken. Only the most effective insecticides should be used to avoid ineffective control and/or promotion of IR. Pyrethroids and organophosphates are the most commonly used insecticides for mosquito control. Here, the efficacy of two active ingredients (AIs; permethrin [pyrethroid], chlorpyrifos [organophosphate]), two formulated products (FPs; Biomist [AI: permethrin]) and (Mosquitomist [AI: chlorpyrifos]), and three synergists (piperonyl butoxide, diethyl maleate, S-S-S-tributyl phosphorotrithioate) was evaluated in two Ae. aegypti colonies (pyrethroid resistant and susceptible). Mosquitomist was most effective against the pyrethroid-resistant colony (100% mortality at diagnostic time). Pre-exposure to synergists did not increase the efficacy of AIs against the pyrethroid-resistant colony. Further research is needed to discover how synergists may affect the efficacy of insecticides when used on pyrethroid-resistant mosquitoes.

中文翻译：

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埃及伊蚊（Diptera：Culicidae）对有机磷酸盐和拟除虫菊酯的抗性评估：增效剂会影响死亡率吗？

埃及伊蚊（Aedes aegypti）是寨卡病毒，登革热，黄热病和基孔肯雅病毒的主要载体。用于灭蚊的杀虫剂可以帮助预防媒介传播疾病的传播。但是，在采取控制措施之前确定杀虫剂抗药性（IR）状态至关重要。仅应使用最有效的杀虫剂，以避免无效的控制和/或促进IR。拟除虫菊酯和有机磷酸盐是控制蚊子最常用的杀虫剂。在这里，两种活性成分（AIs；苄氯菊酯[拟除虫菊酯]，毒死rif [有机磷酸盐]），两种配方产品（FPs； Biomist [AI：氯菊酯]）和（驱蚊药[AI：毒死rif]）和三种协同剂（哌啶基）的功效丁醇，马来酸二乙酯，SSS-三硫代磷酸三丁酯）进行了两次评估e 埃及人菌落（对拟除虫菊酯有抗药性和易感性）。蚊虫对拟除虫菊酯抗性菌落最有效（诊断时死亡率为100％）。预先暴露于增效剂并没有增加AIs对拟除虫菊酯抗性菌落的功效。需要进一步的研究来发现增效剂在对拟除虫菊酯具有抗性的蚊子上使用时如何影响杀虫剂的功效。