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Cu(II)‐Catalyzed Ortho‐Selective Amination of Simple Phenols with O‐Benzoylhydroxylamines
Israel Journal of Chemistry ( IF 2.3 ) Pub Date : 2020-02-26 , DOI: 10.1002/ijch.201900171
Nan‐Qi Shao 1 , Zhi‐Li Yao 1 , Dong‐Hui Wang 1
Affiliation  

A Cu(II)‐catalyzed ortho‐selective amination of simple phenols with O‐benzoylhydroxylamines has been developed, which provides access to 2‐aminophenols under mild conditions. Various functional groups on the phenol and electrophilic amine are compatible, and the protocol typically delivers the products in moderate to good yields. The mechanistic detail of this process are discussed.

中文翻译:

Cu(II)催化邻苯甲酰基羟胺对简单酚的邻位选择性胺化

已经开发了一种铜(II)催化的简单酚与苯甲酰基羟胺的邻位选择性胺化反应,该条件可在温和条件下获得2-氨基苯酚。苯酚和亲电子胺上的各种官能团是相容的,并且该方案通常以中等到良好的产率提供产物。讨论了此过程的机械细节。
更新日期:2020-02-26
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