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Break on Through: Golgi-Derived Vesicles Aid in Mitochondrial Fission.
Cell Metabolism ( IF 27.7 ) Pub Date : 2020-06-02 , DOI: 10.1016/j.cmet.2020.05.010 Megan L Rasmussen 1 , Gabriella L Robertson 1 , Vivian Gama 2
中文翻译:
突破:线粒体裂变中高尔基衍生的囊泡的帮助。
更新日期:2020-06-02
Cell Metabolism ( IF 27.7 ) Pub Date : 2020-06-02 , DOI: 10.1016/j.cmet.2020.05.010 Megan L Rasmussen 1 , Gabriella L Robertson 1 , Vivian Gama 2
Affiliation
Mitochondrial fission is sustained through contact with several organelles, including the endoplasmic reticulum, lysosomes, and the actin cytoskeleton. Nagashima et al. (2020) now demonstrate that PI(4)P-containing Golgi-derived vesicles also modulate mitochondrial fission, driven by Arf1 and PI(4)KIIIβ activity, identifying a new organelle contact involved in maintaining mitochondrial homeostasis.
中文翻译:
突破:线粒体裂变中高尔基衍生的囊泡的帮助。
线粒体裂变通过与多个细胞器接触而得以维持,这些细胞器包括内质网,溶酶体和肌动蛋白细胞骨架。长岛等。(2020)现在证明含有PI(4)P的高尔基体来源的小泡还可以调节由Arf1和PI(4)KIIIβ活性驱动的线粒体裂变,从而确定了涉及维持线粒体稳态的新细胞器接触。