Synthetic nanostructured hydroxyapatite is promising for a wide range of problems in reconstructive medicine and implantology, as well as in cosmetology and dentistry. By changing the synthesis conditions, it is possible for each specific application to adjust the characteristics of the material in accordance with the task. Samples of nanostructured hydroxyapatite with different compositions and granule size were obtained by chemical deposition followed by spray drying with ultrasound treatment. Analysis of the hemocompatibility of materials in experiments with mononuclear leukocytes and mouse blood erythrocytes showed that the obtained granule samples at a concentration of 40 mg per 2 mL of cell suspension are hemocompatible in all studied parameters, regardless of the size and composition of spheres.

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各种尺寸的纳米羟基磷灰石球的血液相容性评估

合成的纳米结构羟基磷灰石有望在重建医学和种植学以及美容学和牙科领域中引起广泛的问题。通过更改合成条件，每个特定的应用程序都可以根据任务调整材料的特性。通过化学沉积，然后通过超声处理进行喷雾干燥，获得具有不同组成和颗粒尺寸的纳米结构羟基磷灰石样品。在单核白细胞和小鼠血液红细胞的实验中，材料的血液相容性分析表明，所获得的颗粒样品在每2 mL细胞悬浮液中的浓度为40 mg，在所有研究参数中均具有血液相容性，而与球体的大小和组成无关。