Abstract—

Complex studies combining X-ray diffraction analysis, thermophysical and dynamic measurements by the probe method, and scanning electron microscopy have been performed. The specific features of the crystalline and amorphous structures of ultrathin fibers based on poly(3-hydroxybutyrate) (PHB) containing tetraphenylporphyrin (TPP) complexes with manganese (in the form of MnCl₂), zinc, and iron (in the form of FeCl₃) in minor concentrations (0–5%) have been considered. It is shown that the addition of these complexes to PHB fibers changes the fiber morphology, and an increase in crystallinity and a symbatic decrease in the molecular mobility in dense and loose amorphous PHB regions are observed in the following sequence: PHB/TPP, PHB/Zn–TPP, PHB/MnCl₂–TPP, and PHB/FeCl₃–TPP. The effect of temperature on fibers (their annealing at 140°C) sharply increases the crystallinity and molecular mobility in amorphous regions of the fibers. Their exposure in an aqueous medium at 70°C leads to an increase in the melting enthalpy and retardation of the molecular dynamics only in the initial PHB; in modified fibers, however, this exposure reduces the enthalpy significantly. In this case, the molecular mobility of chains in amorphous regions increases. The fibrous materials obtained have bactericidal properties and should find application in designing new therapeutic systems of antibacterial and antitumor action.

中文翻译：

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四苯基卟啉与金属铁，锰和锌配合物改性的聚（3-羟基丁酸酯）超细纤维的比较结构动力学分析

摘要—

结合X射线衍射分析，探针法进行热物理和动态测量以及扫描电子显微镜的综合研究已经进行。基于含四苯基卟啉（TPP）与锰（以MnCl ₂的形式），锌和铁（以FeCl的形式）的聚（3-羟基丁酸酯）（PHB）的超细纤维的晶体和非晶结构的特定特征₃）已考虑过少量（0–5％）。结果表明，向PHB纤维中添加这些复合物会改变纤维形态，并在以下顺序中观察到在致密和疏松无定形PHB区域中结晶度的增加和分子迁移率的象征性下降：PHB / TPP，PHB / Zn–TPP，PHB / MnCl ₂-TPP和PHB / FeCl ₃ -TPP。温度对纤维的影响（它们在140°C退火）会急剧增加纤维非晶态区域的结晶度和分子迁移率。它们仅在初始PHB中暴露于70°C的水介质中会导致熔融焓增加和分子动力学延迟; 但是，在改性纤维中，这种接触会显着降低焓。在这种情况下，非晶区域中链的分子迁移率增加。所获得的纤维材料具有杀菌性能，应该在设计具有抗菌和抗肿瘤作用的新治疗系统中得到应用。