Abstract

In the present paper, Fe₃O₄@SiO₂/GO nanocomposite was synthesized and used to modify a graphite screen-printed electrode. This modified electrode was used to determine levodopa in the presence of tryptophan. Differential pulse voltammetry data showed that the obtained anodic peak currents were linearly dependent on levodopa concentrations in a range of 0.5–800.0 µM, with the detection limit of 0.09 µM. This novel sensor has several advantages such as rapid response, high stability, reproducibility, and high sensitivity. In addition, this proposed sensor was used to determine levodopa and tryptophan in human blood serum and urine samples.

中文翻译：

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磁性核壳Fe 3 O 4 @SiO 2 / GR纳米复合材料修饰石墨丝网印刷电极对色氨酸中左旋多巴的电化学感应

摘要

本文合成了Fe ₃ O ₄ @SiO ₂ / GO纳米复合材料，并将其用于修饰石墨丝网印刷电极。该修饰的电极用于在色氨酸存在下测定左旋多巴。差分脉冲伏安法数据显示，所获得的阳极峰值电流在0.5–800.0 µM范围内与左旋多巴浓度线性相关，检出限为0.09 µM。这种新颖的传感器具有诸如快速响应，高稳定性，可再现性和高灵敏度等优点。此外，该传感器可用于测定人血清和尿液样品中的左旋多巴和色氨酸。