Abstract

The objective of the survey is to reveal the effects of a dysfunctional relationship between the gonadal steroids (progesterone and 17β-estradiol) on occurrence of inflammatory diseases (endometriosis and metritis-mastitis-agalactia) in sows in the postpartum period. The surveys were carried out with 27 sows at 106–107 days of gestation, measuring the concentrations of progesterone and 17β-estradiol on the seventh, fifth, third, and first days before the expected farrowing date and during parturition. The subsequent retrospective analysis of the results of the collected measurements was performed depending on the course of the postpartum period in sows. It was ascertained that the progesterone blood concentrations the 3 days before the farrowing date and during parturition in sows affected with postpartum diseases were higher by 48.7 (p < 0.01) and 31.1% (p < 0.05), respectively, than that in the animals that remained healthy after farrowing, while the estradiol concentrations were lower by 10.1 and 21.0%, respectively. In addition, progesterone-to-estradiol ratio variables were 1.6-fold (p < 0.01) and 1.7-fold (p < 0.01) higher, respectively. This allows for the consideration that a dysfunctional relationship between the hormones in sows at the end of gestation and during parturition can be one of the factors causing the pathological processes of an inflammatory type in the postpartum period. In addition, it is eligible to apply the progesterone-to-estradiol ratio as a criterion for predicting the risk for disease incidence.

中文翻译：

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预测生殖道炎症过程中母猪性腺甾体浓度的参数

摘要

该调查的目的是揭示性腺类固醇（孕激素和17β-雌二醇）之间功能失调的关系对产后母猪发炎性疾病（子宫内膜异位和子宫炎-乳腺炎-乳腺炎）的影响。在妊娠106-107天时对27头母猪进行了调查，在预期分娩日期的第七，第五，第三和第一天和分娩期间测量了孕酮和17β-雌二醇的浓度。根据母猪产后时期的过程，对收集的测量结果进行随后的回顾性分析。经确定，受产后疾病影响的母猪在分娩日期前三天和分娩期间的孕酮血浓度升高了48.7％（分别比分娩后保持健康的动物的p <0.01）和31.1％（p <0.05），而雌二醇的浓度分别降低了10.1和21.0％。此外，孕酮与雌二醇的比例变量分别高1.6倍（p <0.01）和1.7倍（p <0.01）。这考虑了妊娠结束时和分娩时母猪体内激素之间功能失调的关系可能是导致产后炎症性病理过程的因素之一。此外，有资格将孕酮与雌二醇之比作为预测疾病发病风险的标准。