Abstract

Complexes of a cationic pyridylphenylene dendrimer with solid and fluid anionic liposomes are prepared. Adsorption of the dendrimer on the surface of liposomes causes the neutralization of their surface charge and enlargement of the dendrimer–liposome aggregates. In interacting with fluid liposomes, the dendrimer does not induce the transition of negatively charged lipid molecules from the inner monolayer into the outer one (flip-flop). The prepared liposome–dendrimer aggregates contain 80 dendrimer molecules per liposome.

中文翻译：

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阴离子脂质体与阳离子吡啶基亚苯基树枝状大分子之间的相互作用

摘要

制备了阳离子吡啶基亚苯基树枝状大分子与固体和流体阴离子脂质体的复合物。树枝状聚合物在脂质体表面的吸附会中和其表面电荷，并使树枝状聚合物-脂质体聚集体增大。与流体脂质体相互作用时，树枝状聚合物不会诱导带负电荷的脂质分子从内部单分子层过渡到外部单分子层（触发器）。制备的脂质体-树状大分子聚集体每个脂质体包含80个树状大分子。