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Formation of Lipofuscin in Drosophila after Exposure to Elevated Temperatures and UV Radiation
Biophysics Pub Date : 2020-01-01 , DOI: 10.1134/s000635092001011x
A. E. Krylova , A. V. Chaplygina , N. L. Vekshin

Abstract —A spectroscopic study of the manner in which exposure to elevated temperature or intense UV radiation leads to the occurrence of lipofuscin debris in the bodies and heads of Drosophila melanogaster ( vestigial ) has been performed. A 1-h exposure to elevated temperature (48°C) or UV radiation led to the degradation of tryptophan residues in Drosophila bodies and heads, which is associated with the appearance of blue fluorescence of thermos-lipofuscin or photo-lipofuscin, respectively. This evidence suggests that tryptophan residues are actively involved in the formation of these lipofuscins. The thermal and photo destruction of the retinal of eye rhodopsin has also been observed.

中文翻译:

暴露于高温和紫外线辐射后果蝇中脂褐素的形成

摘要 —对暴露于高温或强紫外线辐射导致黑腹果蝇(退化)身体和头部出现脂褐素碎片的方式进行了光谱研究。暴露于高温 (48°C) 或紫外线辐射 1 小时会导致果蝇身体和头部中的色氨酸残基降解,这分别与嗜热脂褐素或光脂褐素的蓝色荧光的出现有关。这一证据表明色氨酸残基积极参与这些脂褐素的形成。还观察到眼视紫质视网膜的热和光破坏。
更新日期:2020-01-01
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