Abstract

Increasing application of pesticides and their toxicity made it essential to develop reliable and accurate methods of their trace quantification. This research was aimed to develop an electrochemical nanocomposite sensor based on molecularly imprinted polymer (MIP) for selective and sensitive determination of carbofuran. The proposed sensor was made based on incorporation of carbofuran MIP in the carbon paste. The square wave voltammetric (SWV) method was applied for the electrochemical measurements. The experimental design was then used to optimize parameters affecting the sensor response according to selected experimental domain. The obtained linear range after optimization of the parameters was from 1 × 10^–9 to 1 × 10^–6 M. The calculated detection limit was 3 × 10^–10 M. Under optimized extraction and determination conditions, the proposed modified sensor indicated the considerable sensitivity and selectivity to determine carbofuran in some real samples (human urine, tap and river water) without any special sample pre-treatment before the analysis.

中文翻译：

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分子印迹聚合物传感器，多变量优化，用于伏安法测定生物和环境样品中的呋喃丹农药

摘要

农药及其毒性的日益增加使其必须开发可靠而准确的痕量定量方法。这项研究旨在开发一种基于分子印迹聚合物（MIP）的电化学纳米复合传感器，用于选择性和灵敏地测定呋喃丹。所提出的传感器是基于在碳糊中掺入了呋喃呋喃MIP而制成的。方波伏安法（SWV）用于电化学测量。然后根据所选的实验域，使用实验设计来优化影响传感器响应的参数。优化参数后获得的线性范围为1×10 ^–9到1×10 ^–6M.计算的检测限为3×10 ^–10M。在优化的提取和测定条件下，建议的改进型传感器显示出在某些实际样品（人尿，自来水和河水中）中测定呋喃丹的相当高的灵敏度和选择性，而无需任何特殊处理样品在分析之前进行预处理。