Abstract—

Carbonate-containing hydroxyapatite has been synthesized from prototype human synovial fluid in the presence of proline. The resultant powders have been shown to contain 61 to 71 wt % the amino acid. The presence of proline in the model solution has been shown to change the crystallinity and specific surface area of the samples, without influencing the composition or crystallite size of the solid phase. High amino acid concentrations lead to the formation of poorly crystallized composites consisting of smaller nanocrystals. The dissolution of the samples in a 0.9% NaCl solution and an acetate buffer has been shown to be a two-step process. The highest solubility in weakly acidic solutions has been demonstrated by the precipitates containing the amino acid.

中文翻译：

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脯氨酸存在下制备碳酸盐羟基磷灰石的结构形态特征及溶解行为

摘要—

已经在脯氨酸存在下从原型人滑液合成了含碳酸盐的羟基磷灰石。已显示所得粉末包含61至71重量％的氨基酸。已显示模型溶液中脯氨酸的存在会改变样品的结晶度和比表面积，而不会影响固相的组成或微晶尺寸。高氨基酸浓度会导致由较小的纳米晶体组成的结晶不良的复合材料的形成。样品在0.9％NaCl溶液和乙酸盐缓冲液中的溶解已显示为两步过程。含有氨基酸的沉淀物证明了在弱酸性溶液中的最高溶解度。