Abstract

Materials based on calcium sulfate in which Na⁺ or K⁺ cations were substituted to a concentration of 5, 10, or 20 mol % for Ca²⁺ cations were synthesized and studied. The introduction of Na⁺ produced materials with the structure of calcium sulfate hemihydrate and dihydrate, and the incorporation of potassium yielded a mixture of calcium sulfates with various contents of chemically bound water and sulfates in which potassium cations formed compounds with different Ca : K ratios. The doping of calcium sulfate with sodium and potassium cations increased the solubility of materials by a factor of 1‒2 and 3‒4, respectively. The developed materials are promising in medical applications for filling bone tissue defects and also for using as a cement matrix for targeted drug delivery.

中文翻译：

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钠钾掺杂对硫酸钙合成中相形成的影响

摘要

合成并研究了基于硫酸钙的材料，其中Na ⁺或K ⁺阳离子被替换为Ca ²⁺阳离子的浓度为5、10或20 mol％。钠⁺的介绍生产出具有半水合硫酸钙和二水合硫酸钙结构的材料，钾的掺入产生了具有不同化学结合水含量和硫酸根含量的硫酸钙混合物，其中钾阳离子形成具有不同Ca：K比的化合物。钠和钾阳离子对硫酸钙的掺杂分别使材料的溶解度增加了1‒2和3‒4。所开发的材料在医学应用中有望填补骨组织缺损，并可用作水泥基体以用于靶向药物输送。