This work presents a novel structure of surface plasmon resonance (SPR) sensor for urine glucose detection. The structure consists of four layers namely gold, molybdenum disulfide (MoS 2 ), h-BN (hexagonal boron nitride), and graphene. Here, the few-layer h-BN is used as a capping layer over the MoS 2 layer. The present sensor performance has been evaluated for sensitivity, quality parameter, resonance angle shift, and accuracy of detection. Sensitivity for urine glucose concentration of 0–15 mg/dl (normal range), 0.625 g/dl, 1.25 g/dl, 2.5 g/dl, 5 g/dl and 10 g/dl are found to be 180 degree/RIU, 183.34 degree/RIU, 185.71 degree/RIU, 187.5 degree/RIU, 190.9 degree/RIU and 194.12 degree/RIU respectively. The corresponding values of quality parameters and detection accuracy are observed 14.88 /RIU, 15.15 /RIU, 15.35 /RIU, 15.5 /RIU, 15.78 /RIU, 16.04 /RIU and 0.07448, 0.09091, 0.10744, 0.12397, 0.17355, 0.27273 respectively. Hence, these enhanced performances of the present SPR biosensor makes this structure suitable for urine glucose detection as well as open a new platform in the field of medical science.

中文翻译：

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用于尿糖检测的高灵敏度表面等离子体共振 (SPR) 传感器的建模

这项工作提出了一种用于尿糖检测的表面等离子体共振 (SPR) 传感器的新型结构。该结构由四层组成，即金、二硫化钼（MoS 2 ）、h-BN（六方氮化硼）和石墨烯。这里，少层 h-BN 用作 MoS 2 层上的覆盖层。目前的传感器性能已针对灵敏度、质量参数、共振角偏移和检测精度进行了评估。发现对 0–15 mg/dl（正常范围）、0.625 g/dl、1.25 g/dl、2.5 g/dl、5 g/dl 和 10 g/dl 的尿葡萄糖浓度的敏感性为 180 度/RIU，分别为 183.34 度/RIU、185.71 度/RIU、187.5 度/RIU、190.9 度/RIU 和 194.12 度/RIU。观察到的质量参数和检测精度的对应值为14.88 /RIU、15.15 /RIU、15.35 /RIU、15.5 /RIU、15.78 /RIU、16。04 /RIU 和 0.07448、0.09091、0.10744、0.12397、0.17355、0.27273。因此，本 SPR 生物传感器的这些增强性能使该结构适用于尿糖检测，并在医学科学领域开辟了一个新平台。