Targeting interleukin (IL)−6 or its receptor for the treatment of inflammatory disease is an attractive approach to the management of complex inflammatory diseases, especially those with a systemic component to their presentation and comorbidity. Biological drugs that target IL-6 receptor are already in clinical practice. Recently, more agents are emerging from clinical trials that block distinct parts of the IL-6/IL-6R pathway. In this edition, Jones et al explore the rich diversity of biology mediated by IL-6. …

中文翻译：

---

考虑IL-6

靶向白介素（IL）-6或其受体治疗炎性疾病是治疗复杂炎性疾病的一种有吸引力的方法，尤其是那些对它们的表现和合并症具有系统性成分的疾病。靶向IL-6受体的生物药物已经在临床实践中。最近，临床试验中出现了更多的药物，它们阻断了IL-6 / IL-6R途径的不同部分。在此版本中，Jones等人探索了IL-6介导的生物学多样性。…