Abstract Introduction The prohibition of antibiotic use in edible snails obligates breeders to treat bacterial infections by different means, of which a common one is a bath in Gram-positive– and partially Gram-negative–bactericidal ethacridine lactate solution. The aim of the study was to determine the effect of bathing Cornu aspersum Müller snails in a 0.1% aqueous solution of ethacridine lactate on selected physiological parameters of haemolymph. Material and Methods The study included 80 snails, divided into two equal groups (study and control). The study group was subjected to bathing in ethacridine lactate and the control group to bathing in tap water. Both groups were treated daily for seven days. The number of haemocytes in the haemolymph, the activity of alanine (ALT) and aspartate (AST) aminotransferases, and the concentration of urea were determined. Results In the study group, after exposure to ethacridine lactate solution an increase in ALT activity, changes in the De Ritis ratio, an increase in the amount of haemocytes, and a decrease in body weight were found. No such changes were detected in the control group snails or in animals after the first bath. Conclusion Multiple applications of a 0.1% ethacridine lactate bath may adversely affect Cornu aspersum Müller snails.

中文翻译：

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0.1%乳酸依沙吖啶水溶液沐浴对山茱萸食用蜗牛生理参数的影响

摘要 简介 禁止在食用蜗牛中使用抗生素迫使养殖者通过不同的方式治疗细菌感染，其中一种常见的方法是在革兰氏阳性和部分革兰氏阴性的杀菌乳酸依沙吖啶溶液中洗澡。该研究的目的是确定在 0.1% 乳酸依沙吖啶水溶液中沐浴 Cornu aspersum Müller 蜗牛对选定的血淋巴生理参数的影响。材料和方法 该研究包括 80 只蜗牛，分为两组（研究组和对照组）。研究组用依沙吖啶乳酸沐浴，对照组用自来水沐浴。两组均每天治疗 7 天。血淋巴中血细胞的数量，丙氨酸 (ALT) 和天冬氨酸 (AST) 氨基转移酶的活性，并测定尿素浓度。结果在研究组中，在接触依沙吖啶乳酸溶液后，发现 ALT 活性增加，De Ritis 比率发生变化，血细胞数量增加，体重下降。在第一次沐浴后，对照组蜗牛或动物中没有检测到这种变化。结论 多次使用 0.1% 依沙吖啶乳酸浴可能会对 Cornu aspersum Müller 蜗牛产生不利影响。