Abstract Green synthesized nanoparticles from plant extracts are being used in various biomedical applications, particularly because of their bactericidal and cytotoxic activities. In this study, silver nanoparticles (AgNPs) were successfully synthesized from the Rosmarinus officinalis aqueous leaf extract. Different spectroscopic and microscopic analyses such as ultraviolet-visible (UV-vis) spectroscopy, Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy, and energy-dispersive X-ray spectroscopy were performed to verify the biosynthesized AgNPs in our sample. The formation of nanosilver particles was preliminarily confirmed by UV-vis spectroscopy at 400 nm. The presence of carboxylic or amide groups was confirmed by FTIR, for the reduction of the silver ion. Transmission electron microscopy confirmed a particle size of 12–22 nm. The prepared AgNPs showed good antibacterial activity against human pathogens and good cytotoxic activity against the human breast cancer cell line (MDA MB 231). The nanoparticles prepared from R. officinalis can be used for various biomedical applications.

中文翻译：

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迷迭香叶绿色合成纳米银的杀菌和细胞毒特性

摘要 来自植物提取物的绿色合成纳米颗粒正用于各种生物医学应用，特别是因为它们具有杀菌和细胞毒活性。在这项研究中，银纳米粒子 (AgNPs) 从迷迭香叶水提取物中成功合成。进行了不同的光谱和显微镜分析，如紫外-可见 (UV-vis) 光谱、傅里叶变换红外光谱 (FTIR)、扫描电子显微镜和能量色散 X 射线光谱，以验证我们样品中生物合成的 AgNP。纳米银粒子的形成通过紫外可见光谱在 400 nm 处初步证实。FTIR 证实了羧基或酰胺基团的存在，用于银离子的还原。透射电子显微镜证实粒径为 12-22 nm。制备的 AgNPs 对人类病原体显示出良好的抗菌活性，对人类乳腺癌细胞系 (MDA MB 231) 显示出良好的细胞毒活性。从厚朴制备的纳米粒子可用于各种生物医学应用。