A variety of polymerizations has long been performed in continuous flow reactors on an industrial scale; comparatively, on smaller scales, continuous polymerization methods have only gained significant attention in recent years. Yet, within the last decade, the field has moved from the rare occurrence of flow reactors to their abundant use today. A wide variety of polymer reactions have been performed in a continuous fashion on small and intermediate scales. The advantages of applying flow chemistry principles for polymer reactions include increased reproducibility and synthetic precision, significant increases in reaction performances for photochemical reactions, the ability to couple reactors to create complex materials in a single reactor pass, as well as the unique combination of online monitoring and machine learning. In this review we give a comprehensive overview of polymer reactions being carried out in continuous flow reactors to date. The development of the field is discussed, concluding with the most recent examples on automated polymer synthesis, reactor telescoping and nanoparticle synthesis. Finally, the design of flow reactors is discussed to help newcomers contribute to the current and future developments in the field.

长期以来，已经在连续流反应器中以工业规模进行了各种聚合反应。相对而言，在较小规模上，连续聚合方法近几年才受到广泛关注。然而，在过去十年中，该领域已从稀有的流动反应器转变为当今的大量使用。已经以中小规模连续地进行了各种各样的聚合物反应。将流动化学原理应用于聚合物反应的优势包括可重复性和合成精度的提高，光化学反应的反应性能显着提高，能够在单个反应器通道中将反应器耦合以生成复杂材料的能力以及在线监控的独特组合和机器学习。在这篇综述中，我们对迄今为止在连续流反应器中进行的聚合物反应进行了全面概述。讨论了该领域的发展，并提供了有关自动聚合物合成，反应器伸缩和纳米颗粒合成的最新示例。最后，讨论了流动反应器的设计，以帮助新来者为该领域的当前和未来发展做出贡献。