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Complex Meniscus Tears Treated with Collagen Matrix Wrapping and Bone Marrow Blood Injection: Clinical Effectiveness and Survivorship after a Minimum of 5 Years' Follow-Up.
CARTILAGE ( IF 2.7 ) Pub Date : 2020-06-01 , DOI: 10.1177/1947603520924762
Kinga Ciemniewska-Gorzela 1 , Paweł Bąkowski 1 , Jakub Naczk 1 , Roland Jakob 2, 3 , Tomasz Piontek 1, 4
Affiliation  

Purpose. To determine the 5-year success rate of the “all-inside” technique of arthroscopic meniscus suture and collagen membrane wrapping along with bone marrow blood injection, to evaluate the progression of degenerative changes and the impact of simultaneous anteriro cruciate ligament (ACL) reconstruction. Methods. Fifty-four consecutive patients with complex meniscal tears were treated with the previously described technique. The subjective scores (International Knee Documentation Committee 2000, Lysholm, EQ-5D-5L) and Barret clinical criteria of meniscal healing were recorded. Magnetic resonance images (MRIs) were assessed at 2 and 5 years postoperatively, using the Whole-Organ Magnetic Resonance Imaging Score (WORMS) criteria. Kaplan-Meier survival analyses were performed in order to assess the survivorship after the index procedure. Thirty-nine patients were divided into 2 groups: group A—isolated meniscus repair and group B—meniscus repair with concurrent ACL reconstruction. Results. Fifty-four patients were treated and 44 were available for analysis. There was a statistically significant improvement in subjective scores and clinical assessment between the preoperative, 2-year follow-up, and 5-year follow-up time points. EQ-5D-5L utility value was 0.9 ± 1 at final follow-up. The WORMS osteoarthritis severity grade had increased from 6.9 ± 5.0 points at the 2-year follow-up to 11.1 ± 9.6 points at the 5-year follow-up (P < 0.001). There was a significant difference between the groups after 60 months. The overall survival rate at final follow-up was 88%. Conclusions. The treatment option evaluated in this study has shown very good mid-term clinical and MRI-based outcomes as well as a favorable survival rate. Simultaneous ACL reconstruction is likely a factor for osteoarthritis progression.



中文翻译:

用胶原基质包裹和骨髓血注射治疗的复杂半月板撕裂:至少 5 年随访后的临床疗效和存活率。

目的。确定关节镜下半月板缝合和胶原膜包扎联合骨髓血注射“全内”技术的5年成功率,评估退行性改变的进展情况以及同时前交叉韧带(ACL)重建的影响. 方法. 连续 54 名患有复杂半月板撕裂的患者接受了上述技术的治疗。记录主观评分(International Knee Documentation Committee 2000, Lysholm, EQ-5D-5L)和半月板愈合的 Barret 临床标准。使用全器官磁共振成像评分 (WORMS) 标准在术后 2 年和 5 年评估磁共振图像 (MRI)。进行 Kaplan-Meier 生存分析以评估指数程序后的生存情况。39 例患者分为 2 组:A 组——孤立半月板修复和 B 组——半月板修复同时 ACL 重建。结果. 54 名患者接受了治疗,44 名可用于分析。在术前、2 年随访和 5 年随访时间点之间,主观评分和临床评估有统计学意义的改善。最终随访时 EQ-5D-5L 效用值为 0.9 ± 1。WORMS 骨关节炎严重程度从 2 年随访时的 6.9 ± 5.0 分增加到 5 年随访时的 11.1 ± 9.6 分(P < 0.001)。60个月后,各组之间存在显着差异。最终随访时的总生存率为 88%。结论. 本研究评估的治疗方案显示出非常好的中期临床和基于 MRI 的结果以及良好的生存率。同时 ACL 重建可能是骨关节炎进展的一个因素。

更新日期:2020-06-01
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