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Hypolipidemic and Hypoglycaemic Effect of Wholemeal Bread with Amaranth (Amaranthus dubius Mart. ex Thell.) on Sprague Dawley Rats.
Foods ( IF 4.7 ) Pub Date : 2020-06-01 , DOI: 10.3390/foods9060707 Adriana Beatriz Sánchez-Urdaneta 1, 2 , Keyla Carolina Montero-Quintero 3 , Pedro González-Redondo 4 , Edgar Molina 3 , Belkys Bracho-Bravo 5 , Rafael Moreno-Rojas 6
Foods ( IF 4.7 ) Pub Date : 2020-06-01 , DOI: 10.3390/foods9060707 Adriana Beatriz Sánchez-Urdaneta 1, 2 , Keyla Carolina Montero-Quintero 3 , Pedro González-Redondo 4 , Edgar Molina 3 , Belkys Bracho-Bravo 5 , Rafael Moreno-Rojas 6
Affiliation
The effect of consuming breads made with wheat flour and Amaranth (Amaranthus dubius Mart. ex Thell.) wholemeal flour on Sprague Dawley rats with hyperlipidaemia and hyperglycaemia induced through feeding was studied. Four diets were provided: control (CD: Ratarina®), commercial bread (CBD), bread with 100 g·kg−1 (ABD10) and 200 g·kg−1 (ABD20) amaranth flour. Zoometric and blood chemistry parameters were measured before and after consuming the diets. A completely random factorial design of 2 × 4 × 2 was used. The factors were blood lipids and glucose level (normal, N and elevated, E), diet (CD, CBD, ABD10 and ABD20) and sex (female, F and male, M). The rats consuming ABD10 and ABD20 diets presented the lowest glucose values, although with no differences (p > 0.05) between the groups of elevated blood lipids and glucose rats (E). Triglyceride concentrations decreased in ABD10 and ABD20 treatments in comparison with CD, elevated blood lipids and glucose (E) rats, while ABD10 rats showed lower total cholesterol level than normal (N) rats. The high-density lipoprotein cholesterol values increased in the ABD10 and ABD20 groups (p < 0.05), while it did lower for very low-density lipoprotein cholesterol and cardiac risk index (p < 0.05). In ABD10 and ABD20 treatments, the abdominal circumference decreased in both sexes (p < 0.05) between weeks 23 and 31. In conclusion, consumption of bread with amaranth improved lipid profiles of rats and could help to prevent metabolic and cardiovascular diseases.
中文翻译：
全麦面包与A菜（A菜Dubius Mart。ex Thell。）对Sprague Dawley大鼠的降脂和降血糖作用。
研究了食用小麦粉和A菜（Amaranthus dubius Mart。ex Thell。）全麦粉制成的面包对Sprague Dawley大鼠高脂血症和高血糖症的影响。分别提供四个饮食：对照（CD：Ratarina ®），商业面包（CBD），面包用100g公斤· -1（ABD10）和200克千克· -1（ABD20）mar菜粉。在食用饮食之前和之后测量动物学和血液化学参数。使用2×4×2的完全随机因子设计。这些因素是血脂和血糖水平（正常，N和升高的E），饮食（CD，CBD，ABD10和ABD20）和性别（女性，F和男性，M）。食用ABD10和ABD20饮食的大鼠的血糖值最低，尽管血脂升高的组和葡萄糖大鼠之间没有差异（p > 0.05）（E）。与CD，血脂和葡萄糖（E）大鼠相比，ABD10和ABD20处理的甘油三酸酯浓度降低，而ABD10大鼠的总胆固醇水平低于正常（N）大鼠。在ABD10和ABD20组中，高密度脂蛋白胆固醇值增加（p<0.05），而对于极低密度脂蛋白胆固醇和心脏危险指数却降低了（p <0.05）。在ABD10和ABD20处理中，男女之间的腹围在第23周到31周之间减小（p <0.05）。总之，食用带有mar菜的面包可以改善大鼠的脂质状况，并有助于预防代谢和心血管疾病。
更新日期：2020-06-01
中文翻译：
全麦面包与A菜（A菜Dubius Mart。ex Thell。）对Sprague Dawley大鼠的降脂和降血糖作用。
研究了食用小麦粉和A菜（Amaranthus dubius Mart。ex Thell。）全麦粉制成的面包对Sprague Dawley大鼠高脂血症和高血糖症的影响。分别提供四个饮食：对照（CD：Ratarina ®），商业面包（CBD），面包用100g公斤· -1（ABD10）和200克千克· -1（ABD20）mar菜粉。在食用饮食之前和之后测量动物学和血液化学参数。使用2×4×2的完全随机因子设计。这些因素是血脂和血糖水平（正常，N和升高的E），饮食（CD，CBD，ABD10和ABD20）和性别（女性，F和男性，M）。食用ABD10和ABD20饮食的大鼠的血糖值最低，尽管血脂升高的组和葡萄糖大鼠之间没有差异（p > 0.05）（E）。与CD，血脂和葡萄糖（E）大鼠相比，ABD10和ABD20处理的甘油三酸酯浓度降低，而ABD10大鼠的总胆固醇水平低于正常（N）大鼠。在ABD10和ABD20组中，高密度脂蛋白胆固醇值增加（p<0.05），而对于极低密度脂蛋白胆固醇和心脏危险指数却降低了（p <0.05）。在ABD10和ABD20处理中，男女之间的腹围在第23周到31周之间减小（p <0.05）。总之，食用带有mar菜的面包可以改善大鼠的脂质状况，并有助于预防代谢和心血管疾病。
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