Citrus grandis Osbeck, commonly known as “pomelo” or “shaddock,” is the largest citrus fruit, the peel of which is a well‐known agricultural residual waste. Pomelo peel offers a wide range of components such as essential oils, polysaccharides, and phytochemicals with potential food applications. Utilization of pomelo peel to recover these components is an important step toward agricultural sustainability. This review covers pomelo peel utilization opportunities beyond conventional composting and animal feed production, and critically examines value‐added uses via the recovery of potentially bioactive components. The peel of pomelo accounts for approximately 30% of the total fruit weight and contains phytochemicals, including aroma‐active volatiles, pectin, flavonoids, phenolic acids, carotenoids, coumarins, and polysaccharides. Recovery of these phytochemicals offers an opportunity for value‐added utilization such as the development of enriched or functional foods and nutraceuticals. The health‐promoting and therapeutic potential of pomelo peel extracts and isolated pure compounds have been evaluated through numerous in vitro and in vivo studies that revealed a wide range of bioactivities, including hypolipidemic, hypoglycemic, antioxidant, antimicrobial, anti‐inflammatory, and anticancer effects. Preclinical evidence highlights multifaceted molecular and signaling events that possibly underlie the said bioactive potential. Overall, the pomelo processing industry offers a great opportunity to recover or produce valuable products from the large amounts of residual wastes it generates. It is envisaged that a thorough understanding of the bioactive components of pomelo peel, their functional and nutraceutical applications, and mode of actions will benefit the food industry.

中文翻译：

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柚子皮的价值化：当前利用、植物化学、生物活性和作用机制的综述

柑橘奥斯贝克俗称“柚子”或“柚子”，是最大的柑橘类水果，其果皮是众所周知的农业残留废物。柚皮提供了广泛的成分，如精油、多糖和具有潜在食品应用潜力的植物化学物质。利用柚皮回收这些成分是实现农业可持续性的重要一步。本综述涵盖了传统堆肥和动物饲料生产之外的柚皮利用机会，并通过潜在生物活性成分的回收批判性地研究了增值用途。柚子皮约占果实总重量的 30%，含有植物化学物质，包括芳香挥发物、果胶、黄酮类化合物、酚酸、类胡萝卜素、香豆素和多糖。这些植物化学物质的回收为增值利用提供了机会，例如开发丰富或功能性食品和营养保健品。柚皮提取物和分离的纯化合物的健康促进和治疗潜力已通过大量评估体外和体内研究揭示了广泛的生物活性，包括降血脂、降血糖、抗氧化、抗菌、抗炎和抗癌作用。临床前证据强调了可能构成所述生物活性潜力的多方面分子和信号事件。总的来说，柚子加工业提供了一个很好的机会，可以从它产生的大量残余废物中回收或生产有价值的产品。预计对柚皮的生物活性成分、它们的功能和营养应用以及作用方式的透彻了解将使食品工业受益。