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Dynamic oxygen changes during status epilepticus and subsequent endogenous kindling
Epilepsia ( IF 6.6 ) Pub Date : 2020-06-01 , DOI: 10.1111/epi.16554
Marshal D Wolff 1 , Jordan S Farrell 1, 2 , Morris H Scantlebury 1, 3, 4 , G Campbell Teskey 1, 4
Affiliation  

Brain tissue oxygen (partial oxygen pressure [pO2]) levels are tightly regulated to stay within the normoxic zone, with deviations on either side resulting in impaired brain function. Whereas pathological events such as ischemic attacks and brief seizures have previously been shown to result in pO2 levels well below the normoxic zone, oxygen levels during prolonged status epilepticus (SE) and the subsequent endogenous kindling period are unknown.

中文翻译:


癫痫持续状态和随后的内源性点燃期间的动态氧变化



脑组织氧(氧分压 [pO2])水平受到严格调节,以保持在含氧量正常范围内,任何一方的偏差都会导致脑功能受损。虽然缺血性发作和短暂癫痫发作等病理事件先前已被证明会导致 pO2 水平远低于含氧量正常范围,但长期癫痫持续状态 (SE) 和随后的内源性点燃期间的氧水平尚不清楚。
更新日期:2020-06-01
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