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Protective role of Galectin‐7 for skin barrier impairment in atopic dermatitis
Clinical & Experimental Allergy ( IF 6.3 ) Pub Date : 2020-06-14 , DOI: 10.1111/cea.13672 Takatsune Umayahara 1 , Takatoshi Shimauchi 1 , Manami Iwasaki 1 , Jun-Ichi Sakabe 1 , Masahiro Aoshima 1 , Shinsuke Nakazawa 1 , Tsuyoshi Yatagai 1 , Hayato Yamaguchi 1 , Pawit Phadungsaksawasdi 1 , Kazuo Kurihara 1 , Yoshiki Tokura 1
Clinical & Experimental Allergy ( IF 6.3 ) Pub Date : 2020-06-14 , DOI: 10.1111/cea.13672 Takatsune Umayahara 1 , Takatoshi Shimauchi 1 , Manami Iwasaki 1 , Jun-Ichi Sakabe 1 , Masahiro Aoshima 1 , Shinsuke Nakazawa 1 , Tsuyoshi Yatagai 1 , Hayato Yamaguchi 1 , Pawit Phadungsaksawasdi 1 , Kazuo Kurihara 1 , Yoshiki Tokura 1
Affiliation
Atopic dermatitis (AD) patients have a barrier disorder in association with Th2 dominant skin inflammation. Galectin‐7 (Gal‐7), a soluble unglycosylated lectin, is highly expressed in the stratum corneum of AD patients. However, the biological significance of increased Gal‐7 expression in AD skin lesions remains unclear.
中文翻译：
Galectin-7 对特应性皮炎皮肤屏障损伤的保护作用
特应性皮炎 (AD) 患者具有与 Th2 显性皮肤炎症相关的屏障障碍。Galectin-7 (Gal-7) 是一种可溶性非糖基化凝集素，在 AD 患者的角质层中高度表达。然而，AD皮肤病变中Gal-7表达增加的生物学意义仍不清楚。
更新日期：2020-06-14
中文翻译：
Galectin-7 对特应性皮炎皮肤屏障损伤的保护作用
特应性皮炎 (AD) 患者具有与 Th2 显性皮肤炎症相关的屏障障碍。Galectin-7 (Gal-7) 是一种可溶性非糖基化凝集素，在 AD 患者的角质层中高度表达。然而，AD皮肤病变中Gal-7表达增加的生物学意义仍不清楚。
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