Abstract

The antioxidant activity and protective effect in the toxicity model of H₂O₂ were studied for arachidonic (AA-CHOL), docosahexaenoic (DHA-CHOL), linoleic (Ln-CHOL), and oleic (Ol-CHOL) fatty acids, as well as arachidonoyl dicholine (AA-diCHOL) and O-arachidonoyl bistetramethylaminoisopropanol (ABTAP). AA-CHOL, DHA-CHOL and Ln-CHOL provided a 20% increase in cell survival. AA-CHOL, AA-diCHOL, Ol-CHOL, and ABTAP had a radical-scavenging effect in the ABTS test, approximately equal to the activity of a standard radical scavenger Trolox.

中文翻译：

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花生四烯酸胆碱，其双季铵化类似物和其他酰胆碱的神经保护和抗氧化活性。

摘要

研究了花生四烯酸（AA-CHOL），二十二碳六烯酸（DHA-CHOL），亚油酸（Ln-CHOL）和油酸（Ol-CHOL）脂肪酸在H ₂ O ₂毒性模型中的抗氧化活性和保护作用。以及花生四烯酸二胆碱（AA-diCHOL）和O-花生四烯酸双四甲基氨基异丙醇（ABTAP）。AA-CHOL，DHA-CHOL和Ln-CHOL使细胞存活率提高了20％。AA-CHOL，AA-diCHOL，Ol-CHOL和ABTAP在ABTS测试中具有自由基清除作用，大约等于标准自由基清除剂Trolox的活性。