Background: Delayed treatment of seriously infected patients results in increased mortality. However, antimicrobial therapy for the initial 24 to 48 hours is mostly empirically provided, without evidence regarding the causative pathogen. Whether empiric anti-enterococcal therapy should be administered to treat intra-abdominal infection (IAI) before obtaining culture results remains unknown. We performed a meta-analysis to explore the effects of empiric enterococci covered antibiotic therapy in IAI and the risk factors for enterococcal infection in IAI.

中文翻译：

---

适当经验性抗肠球菌治疗腹腔感染疗效的系统评价和荟萃分析

背景：严重感染患者的延迟治疗会导致死亡率增加。然而，最初 24 至 48 小时的抗菌治疗大多是凭经验提供的，没有关于致病病原体的证据。在获得培养结果之前，是否应给予经验性抗肠球菌治疗来治疗腹内感染 (IAI) 仍然未知。我们进行了一项荟萃分析，以探讨经验性肠球菌覆盖抗生素治疗对 IAI 的影响以及 IAI 中肠球菌感染的危险因素。