Objective . The auditory brainstem response can be recorded non-invasively from scalp electrodes and serves as an important clinical measure of hearing function. We have recently shown how the brainstem response at the fundamental frequency of continuous, non-repetitive speech can be measured, and have used this measure to demonstrate that the response is modulated by selective attention. However, different parts of the speech signal as well as several parts of the brainstem contribute to this response. Here we employ a computational model of the brainstem to elucidate the influence of these different factors. Approach. We developed a computational model of the auditory brainstem by combining a model of the middle and inner ear with a model of globular bushy cells in the cochlear nuclei and with a phenomenological model of the inferior colliculus. We then employed the model to investigate the neural response to continuous speech at different stages in the brainstem...

中文翻译：

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听觉脑干对连续语音反应的计算模型。

目标。可以从头皮电极无创地记录听觉脑干反应，并作为听力功能的重要临床指标。我们最近展示了如何测量连续，非重复性语音的基本频率下的脑干反应，并已使用该量度来证明该反应受到选择性注意的调节。但是，语音信号的不同部分以及脑干的多个部分都会导致这种反应。在这里，我们采用脑干的计算模型来阐明这些不同因素的影响。方法。我们通过将中耳和内耳模型与耳蜗核中的球状丛状细胞模型以及下丘脑的现象学模型相结合，开发了听觉脑干的计算模型。