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A droplet platform capable of handling dissimilar liquids and its application for separation of bacteria from blood.
Biomicrofluidics ( IF 2.6 ) Pub Date : 2020-05-07 , DOI: 10.1063/5.0006111
Jiawei Wu 1 , Huanming Xia 1 , Wei Wang 2 , Yuhao Foo 2 , Zhiping Wang 2 , Hejun Du 3
Affiliation  

For passive droplet generation, multiple parameters such as the fluid viscosities and flow rates of the continuous and discrete phases correlate to each other, raising relevant control difficulties. In the current study, a droplet platform that is capable of handling dissimilar liquids is proposed. Through combining oscillatory flow and electric charge, synchronized generation and forced coalescence of different droplets can be achieved. Its application for the separation of E. coli from blood is tested, which leads to a high capture efficiency with less sample and within a shorter time than usual.

中文翻译:

一种能够处理不同液体的液滴平台及其在细菌与血液分离中的应用。

对于被动液滴的产生,诸如连续相和离散相的流体粘度和流速之类的多个参数彼此相关,从而增加了相关的控制难度。在当前的研究中,提出了一种能够处理不同液体的液滴平台。通过结合振荡流和电荷,可以实现不同液滴的同步生成和强制聚结。测试了其在从血液中分离大肠埃希氏菌的应用,从而可以以比通常更少的样品和更短的时间获得更高的捕获效率。
更新日期:2020-06-30
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