Coronaviruses disease (COVID-19) has caused major outbreaks. A novel variant, SARS-CoV-2, is responsible for COVID-19 pandemic. Clinical presentations and pathological mechanisms of COVID-19 are broad. The respiratory aspect of the disease has been extensively researched. Emerging studies point out the possibility of the central nervous system (CNS) involvement by COVID-19. Here, we discuss the current evidence for CNS involvement in COVID-19 and highlight that the high pathogenicity of SARS-CoV-2 might be due to its neuroinvasive potential.

中文翻译：

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COVID-19患者中枢神经系统受累。

冠状病毒病（COVID-19）引起了重大暴发。一种新的变体SARS-CoV-2导致了COVID-19大流行。COVID-19的临床表现和病理机制广泛。已经对该疾病的呼吸方面进行了广泛的研究。新兴研究指出，COVID-19可能参与中枢神经系统（CNS）。在这里，我们讨论CNS参与COVID-19的当前证据，并强调SARS-CoV-2的高致病性可能是由于其神经侵袭潜能。