Background: Osteoarthritis (OA) is a complex degenerative joint disease that is associated with both genetic and environmental factors. The AKNA gene, located at 9q32, has recently been identified as being associated with knee osteoarthritis (KOA) in the Mexican population. Our aim was to investigate the relationship of common variants in this gene with the risk of KOA in a large Han Chinese population.

中文翻译：

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汉族人群中AKNA基因的常见变异和对膝骨关节炎的敏感性评估。

背景：骨关节炎（OA）是一种复杂的变性关节疾病，与遗传和环境因素有关。该AKNA基因，位于9q32，最近已被确定为与在墨西哥人口膝关节骨性关节炎（KOA）相关联。我们的目的是研究该基因的常见变异与汉族人群中KOA风险的关系。