Background: The evaluation of lymph nodes (LN) by fine-needle aspiration cytology (FNAC) is routinely used in many institutions but it is not uniformly accepted mainly because of the lack of guidelines and a cytopathological diagnostic classification. A committee of cytopathologists has developed a system of performance, classification, and reporting for LN-FNAC. Methods: The committee members prepared a document that has circulated among them five times; the final text has been approved by all the participants. It is based on a review of the international literature and on the expertise of the members. The system integrates clinical and imaging data with cytopathological features and ancillary techniques. The project has received the endorsement and patronage of the International Academy of Cytology and the European Federation of the Cytology Societies. Results: Clinical, imaging, and serological data of lymphadenopathies, indications for LN-FNAC, technical procedures, and ancillary techniques are evaluated with specific recommendations. The reporting system includes two diagnostic levels. The first should provide basic diagnostic information and includes five categories: inadequate/insufficient, benign, atypical lymphoid cells of undetermined/uncertain significance, suspicious, and malignant. For each category, specific recommendations are provided. The second diagnostic level, when achievable, should produce the identification of specific benign or malignant entities and additional information by utilizing ancillary testing. Conclusion: The authors believe that the introduction of this system for performing and reporting LN-FNAC may improve the quality of the procedure, the report, and the communication between cytopathologists and the clinicians. This system may lead to a greater acceptance and utilization of LN-FNAC and to a better interdisciplinary understanding of the results of this procedure.
Acta Cytologica

中文翻译：

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淋巴结细针穿刺细胞病理学的性能，分类和报告的提案：悉尼系统。

背景：通过细针穿刺细胞学检查（FNAC）评估淋巴结（LN）在许多机构中是常规方法，但由于缺乏指南和细胞病理学诊断分类，因此并未被一致接受。细胞病理学家委员会已经开发了LN-FNAC的性能，分类和报告系统。方法：委员会成员编写了一份文件，已在其中分发了五次；最终案文已获得所有参与者的认可。它基于对国际文献的回顾和成员的专业知识。该系统将临床和影像数据与细胞病理学特征和辅助技术整合在一起。该项目获得了国际细胞学学会和欧洲细胞学学会联合会的认可和赞助。结果：淋巴腺病的临床，影像学和血清学数据，LN-FNAC适应症，技术程序和辅助技术均根据具体建议进行了评估。报告系统包括两个诊断级别。第一个应提供基本的诊断信息，包括五类：不确定/不确定，良性，非典型淋巴样细胞，可疑和恶性。对于每个类别，都提供了具体的建议。当可以达到第二个诊断级别时，应通过辅助测试来产生对特定良性或恶性实体的识别以及其他信息。结论：作者认为，引入用于执行和报告LN-FNAC的系统可以改善程序，报告以及细胞病理学家和临床医生之间的交流的质量。该系统可能会导致对LN-FNAC的更多接受和利用，并使对该程序的结果有更好的跨学科理解。
细胞学学报