当前位置: X-MOL 学术Ann. Clin. Microbiol. Antimicrob. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Presence of Borrelia miyamotoi infection in a highly endemic area of Lyme disease.
Annals of Clinical Microbiology and Antimicrobials ( IF 4.6 ) Pub Date : 2020-05-30 , DOI: 10.1186/s12941-020-00364-0
Luis A Marcos 1, 2 , Kalie Smith 1 , Kelsey Reardon 1 , Fredric Weinbaum 3 , Eric D Spitzer 4
Affiliation  

A series of cases in the Northeast of the US during 2013–2015 described a new Borrelia species, Borrelia miyamotoi, which is transmitted by the same tick species that transmits Lyme disease and causes a relapsing fever-like illness. The geographic expansion of B. miyamotoi in the US also extends to other Lyme endemic areas such as the Midwestern US. Co-infections with other tick borne diseases (TBD) may contribute to the severity of the disease. On Long Island, NY, 3–5% of ticks are infected by B. miyamotoi, but little is known about the frequency of B. miyamotoi infections in humans in this particular region. The aim of this study was to perform a chart review in all patients diagnosed with B. miyamotoi infection in Stony Brook Medicine (SBM) system to describe the clinical and epidemiological features of B. miyamotoi infection in Suffolk County, NY. In a 5 year time period (2013–2017), a total of 28 cases were positive for either IgG EIA (n = 19) or PCR (n = 9). All 9 PCR-positive cases (median age: 67; range: 22–90 years) had clinical findings suggestive of acute or relapsing infection. All these patients were thought to have a TBD, prompting the healthcare provider to order the TBD panel which includes a B. miyamotoi PCR test. In conclusion, B. miyamotoi infection should be considered in the differential diagnosis for flu-like syndromes during the summer after a deer tick bite and to prevent labeling a case with Lyme disease.

中文翻译:

在莱姆病的高度流行地区存在宫缩疏螺旋体感染。

2013-2015年期间,美国东北部的一系列病例描述了一种新的疏螺旋体种,宫本疏螺旋体,由传播莱姆病并引起类似发热的疾病的相同tick类传播。宫本芽孢杆菌在美国的地域扩展也扩展到了其他莱姆流行地区,例如美国中西部。与其他壁虱传播疾病(TBD)的合并感染可能会加剧疾病的严重性。在纽约州长岛,3–5%的壁虱感染了宫本芽孢杆菌,但对该地区特定人群中宫本芽孢杆菌的感染频率知之甚少。这项研究的目的是对所有在石溪医学(SBM)系统中被诊断为宫本氏杆菌感染的患者进行图表审查,以描述在萨福克县宫本氏杆菌感染的临床和流行病学特征,纽约。在5年内(2013-2017年),共有28例IgG EIA(n = 19)或PCR(n = 9)阳性。所有9例PCR阳性病例(中位年龄:67;范围:22-90岁)均具有提示急性或复发感染的临床发现。所有这些患者都被认为患有TBD,促使医疗保健提供者订购了包括宫本芽孢杆菌PCR检测在内的TBD检测板。总之,在鹿tick叮咬后的夏季,应在诊断流感样综合征时考虑宫本芽孢杆菌感染,并防止对莱姆病进行标记。所有这些患者均被认为患有TBD,促使医疗保健提供者订购了包括宫本芽孢杆菌PCR测试在内的TBD面板。总之,在鹿tick咬后的夏季,应在诊断流感样综合征时考虑宫本芽孢杆菌感染,并防止将其标记为莱姆病。所有这些患者都被认为患有TBD,这促使医疗保健提供者订购了包括宫本芽孢杆菌PCR测试在内的TBD面板。总之,在鹿tick咬后的夏季,应在诊断流感样综合征时考虑宫本芽孢杆菌的感染,并防止对莱姆病进行标记。
更新日期:2020-05-30
down
wechat
bug