Fragmentation of the Balbiani body in Xenopus oocytes engenders a region extending from the germinal vesicle (GV) towards the vegetal pole that is enriched in mitochondria. This area is later transversed by RNA that is being localized to the vegetal cortex. Inhibition of mitochondrial ATP synthesis prevents the perinuclear formation of these RNA transport granules that can be reversed by the nonhydrolyzable ATP analog, adenosine 5'-(beta,gamma-imido) triphosphate. The protein composition and sensitivity of the transport granules to hexanediol indicate that they are liquid phase condensates. Mitochondria in the remnants of the Balbiani body produce a region of elevated ATP that appears to act as a hydrotrope to support the perinuclear phase transition leading to granule formation.

中文翻译：

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在非洲爪蟾卵母细胞中形成RNA转运颗粒需要Balbiani身体的残留物

非洲爪蟾卵母细胞中Balbiani身体的碎裂形成了一个区域，该区域从生发小泡（GV）向着富含线粒体的植物极延伸。该区域随后被定位于植物皮层的RNA横穿。线粒体ATP合成的抑制作用阻止了这些RNA转运颗粒的核周形成，这种颗粒可以被不可水解的ATP类似物，腺苷5'-（β，γ-亚氨基）三磷酸酯逆转。转运颗粒的蛋白质组成和对己二醇的敏感性表明它们是液相冷凝物。Balbiani体内残余物中的线粒体产生了一个ATP升高的区域，该区域似乎起着水溶助长剂的作用，以支持导致颗粒形成的核周相变。