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Heralding Healthcare Professionals: Recognition of Neurological Deficits in COVID-19.
ACS Chemical Neuroscience ( IF 4.1 ) Pub Date : 2020-05-29 , DOI: 10.1021/acschemneuro.0c00286
Abdul Mannan Baig 1 , Erin C Sanders 2
Affiliation  

The 2019 novel coronavirus disease (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a zoonotic disease that is dominated by pulmonary symptoms. However, recent reports of isolation of the virus from cerebrospinal fluid (CSF) coupled with radiological evidence of zones of necrosis in the brain, have elucidated the neurotropic potential of SARS-CoV-2. The acute respiratory failure seen in patients with COVID-19 is alarming and could be due to the effects of SARS-CoV-2 on the central respiratory regulatory centers in the brainstem. Appropriate interventions can be implemented to prevent severe outcomes of neurological invasion by SARS-CoV-2 to reduce the morbidity and mortality of patients with COVID-19. It is of paramount importance that the scientific community alerts the healthcare professionals of the pieces of evidence that can herald them on the covert neurological deficits in progress in COVID-19.

中文翻译:

预示着医疗保健专业人员:对COVID-19中神经系统缺陷的认识。

严重急性呼吸系统综合症冠状病毒2(SARS-CoV-2)引起的2019年新型冠状病毒疾病(COVID-19)是一种人畜共患疾病,主要由肺部症状引起。但是,最近从脑脊液(CSF)中分离出病毒的报道以及脑部坏死区域的放射学证据阐明了SARS-CoV-2的神经营养潜力。在COVID-19患者中看到的急性呼吸衰竭令人震惊,可能是由于SARS-CoV-2对脑干中央呼吸调节中心的影响。可以采取适当的干预措施,以防止SARS-CoV-2导致严重的神经系统侵犯,从而降低COVID-19患者的发病率和死亡率。
更新日期:2020-05-29
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