CD142 promotes cell mobility, which contributes to carcinogenesis. However, the role of CD142 on colorectal cancer (CRC) mobility is unclear. This study showed that CD142 expression increased in CRC tissues, especially in those with invasion or metastasis. The positive sorting or overexpression of CD142 promoted the invasion and migration of CRC cells. Overall, CD142 may be responsible for CRC mobility.

中文翻译：

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CD142在结直肠癌细胞的迁移中起重要作用

CD142促进细胞迁移，这有助于癌变。但是，CD142在结直肠癌（CRC）迁移中的作用尚不清楚。这项研究表明，CD142表达在CRC组织中增加，特别是在具有侵袭或转移的组织中。CD142的阳性分选或过表达促进了CRC细胞的侵袭和迁移。总体而言，CD142可能负责CRC的移动性。