A Metal‐Free Synthesis of N‐Aryl Oxazolidin‐2‐Ones by the One‐Pot Reaction of Carbon Dioxide with N‐Aryl Aziridines,Advanced Synthesis & Catalysis

当前位置： X-MOL 学术 › Adv. Synth. Catal. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

A Metal‐Free Synthesis of N‐Aryl Oxazolidin‐2‐Ones by the One‐Pot Reaction of Carbon Dioxide with N‐Aryl Aziridines
Advanced Synthesis & Catalysis ( IF 4.4 ) Pub Date : 2020-05-29 , DOI: 10.1002/adsc.202000175
Paolo Sonzini ₁ , Caterina Damiano ₁ , Daniela Intrieri ₁ , Gabriele Manca ₂ , Emma Gallo ₁

Affiliation

The cost‐effective TPPH₂/TBACl‐catalyzed (TPPH₂=dianion of tetraphenyl porphyrin; TBACl=tetrabutyl ammonium chloride) carbon dioxide cycloaddition to N‐aryl aziridines was successful in synthesizing N‐aryl oxazolidin‐2‐ones. A catalytic tandem reaction was also developed, in which N‐aryl aziridines were initially synthesized and then reacted with carbon dioxide without being purified. The procedure occurred with a very high atom economy, molecular nitrogen being the only by‐product of the entire tandem process. In addition, the mechanism of catalytic cycle was investigated by DFT calculations.

中文翻译：

二氧化碳与N-芳基氮丙啶的一锅法反应，无金属合成N-芳基恶唑烷-2-

具有成本效益的TPPH ₂ / TBACl催化（TPPH ₂ =四苯基卟啉的阴离子； TBACl =四丁基氯化铵）二氧化碳环化成N-芳基氮丙啶成功地合成了N-芳基恶唑烷二-2-酮。还开发了催化串联反应，其中最初合成了N-芳基氮丙啶，然后与二氧化碳反应而未纯化。该过程是在非常高的原子经济性下发生的，分子氮是整个串联过程的唯一副产物。另外，通过DFT计算研究了催化循环的机理。

更新日期：2020-07-29

点击分享查看原文

点击收藏

阅读更多本刊最新论文本刊介绍/投稿指南11