Dichlofluanid is a fungicide employed as a booster biocide in antifouling paints, but information its toxicity to aquatic organisms is scarce. This study aims to evaluate biomarker responses in the mussel Perna perna exposed to dichlofluanid. Mussels were exposed to 0 (control), 0.1 μg/L (environmental concentration), 10, and 100 μg/L of dichlofluanid for 24 and 96 h. Byssus formation, oxygen consumption, and oxidative stress response were evaluated in gills and digestive glands. The results demonstrated that even the lowest dichlofluanid concentration causes a reduction in byssus biomass and water content. The higher concentrations caused an acute increase in oxygen consumption, which only returned to control levels after 96 h of exposure. ACAP levels and antioxidant enzyme activities were affected in both tissues with a larger effect observed in gill tissues as demonstrated by the IBR index. The overall results demonstrated that environmentally relevant concentrations of dichlofluanid would be deleterious to aquatic organisms.

Dichlofluanid是一种杀真菌剂，用作防污涂料中的增强杀菌剂，但有关其对水生生物的毒性的信息很少。这项研究旨在评估贻贝Perna perna中的生物标志物反应暴露于二氯氟苯胺。将贻贝暴露于0（对照），0.1μg/ L（环境浓度），10和100μg/ L的二氯氟苯胺暴露24和96 h。在g和消化腺中评估了囊肿形成，耗氧量和氧化应激反应。结果表明，即使最低的二氯氟苯胺浓度也会导致结实的生物量和水含量降低。较高的浓度导致耗氧量急剧增加，仅在暴露96小时后才恢复到控制水平。如IBR指数所示，两种组织中的ACAP水平和抗氧化酶活性均受到影响，在g组织中观察到的影响更大。总体结果表明，与环境有关的敌百氟胺浓度对水生生物有害。