No study has compared the effect of Nigella sativa and Saccharomyces cerevisiae on performance, fecal E. coli and heamatopoitic potential of broiler under experimental condition of Colibacillosis. The aim of the study was to evaluate the protective effect of N. sativa and S. cerevisiae on zootechnical characteristics, fecal microbial load and hematopoietic potential in broiler infected with Escherichia coli. A total of 400 birds (Ross 500) were randomly divided into five groups and five replicates as follow: T1, negative control; T2, positive control (infected with E. coli); T3, infected + 2% N. sativa seed powder; T4, infected + S. cerevisiae; T5, infected + antibiotic (Enrofloxacin 10 mg/kg). At the end of the experimental period, feed intake was lower (P<0.05) in T3 (2644.01±39.8g), T4 (2585.01±51.2g) and T5 (2663.85±32.0g) compared to all other treatments. Weight gain was higher (P>0.05) in T3 (1856.60±59.1g) and T1 (1857.08±48.4g) compared to other treatments. On the basis of overall period, T5 (1.49±0.04) showed higher (P<0.05) FCR as compared to group T1 (1.41±0.01) followed by T3 (1.38±0.02) and T4 (1.37±0.03) but no significant difference (P>0.05) with T2 (1.44±0.02). On day 35 of the trial, T2 (2.69 × 10⁸± 0.54 CFU) showed higher (P<0.05) fecal E. coli population as compared to other treatments. At the end of the trial, there was no significant difference (P>0.05) in red and white blood cells count and hemoglobin concentration among the groups. Results of the present study indicated that supplementation of S. cerevisiae and N. sativa attenuated E. coli infection in broilers.

尚无研究比较Nigella sativa和Saccharomyces cerevisiae在大肠杆菌感染和实验性大肠杆菌病的条件下对肉仔鸡生产性能，粪便大肠杆菌和造血潜能的影响。该研究的目的是评估苜蓿猪笼草和酿酒酵母对感染大肠杆菌的肉鸡的动物技术特性，粪便微生物负荷和造血潜能的保护作用。将总共​​400只家禽（罗斯500只）随机分为五组，重复五次，分别为：T1，阴性对照；T2，阳性对照（感染了大肠杆菌）；T3，感染+ 2％苜蓿种子粉；T4，已感染+ 酿酒酵母; T5，感染+抗生素（恩诺沙星10 mg / kg）。在实验期结束时，与所有其他处理相比，T3（2644.01±39.8g），T4（2585.01±51.2g）和T5（2663.85±32.0g）的采食量较低（P <0.05）。与其他处理相比，T3（1856.60±59.1g）和T1（1857.08±48.4g）的体重增加更高（P> 0.05）。从总时期来看，T5（1.49±0.04）的FCR高于（ T1）组（1.41±0.01），其次是T3（1.38±0.02）和T4（1.37±0.03），但无显着差异（P> 0.05），T2为（1.44±0.02）。在试验的第35天，T2（2.69×10 ⁸ ±0.54 CFU）显示较高的粪便大肠杆菌（P <0.05）人口与其他治疗方法相比。在试验结束时，各组之间的红，白细胞计数和血红蛋白浓度无显着差异（P> 0.05）。本研究的结果表明的，补充的酿酒酵母和N.苜蓿减毒大肠杆菌肉鸡感染。