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Clinical, molecular, and epidemiological characterization of the SARS-CoV-2 virus and the Coronavirus Disease 2019 (COVID-19), a comprehensive literature review.
Diagnostic Microbiology and Infectious Disease ( IF 2.1 ) Pub Date : 2020-05-30 , DOI: 10.1016/j.diagmicrobio.2020.115094
Esteban Ortiz-Prado 1 , Katherine Simbaña-Rivera 1 , Lenin Gómez-Barreno 1 , Mario Rubio-Neira 2 , Linda P Guaman 3 , Nikolaos C Kyriakidis 4 , Claire Muslin 1 , Ana María Gómez Jaramillo 5 , Carlos Barba-Ostria 1 , Doménica Cevallos-Robalino 6 , Hugo Sanches-SanMiguel 1 , Luis Unigarro 7 , Rasa Zalakeviciute 8 , Naomi Gadian 9 , Andrés López-Cortés 10
Affiliation  

Coronaviruses are an extensive family of viruses that can cause disease in both animals and humans. The current classification of coronaviruses recognizes 39 species in 27 subgenera that belong to the family Coronaviridae. From those, at least 7 coronaviruses are known to cause respiratory infections in humans. Four of these viruses can cause common cold-like symptoms. Those that infect animals can evolve and become infectious to humans. Three recent examples of these viral jumps include SARS CoV, MERS-CoV and SARS CoV-2 virus. They are responsible for causing severe acute respiratory syndrome (SARS), Middle East respiratory syndrome (MERS) and the most recently discovered coronavirus disease during 2019 (COVID-19).

COVID-19, a respiratory disease caused by the SARS-CoV-2 virus, was declared a pandemic by the World Health Organization (WHO) on 11 March 2020. The rapid spread of the disease has taken the scientific and medical community by surprise. Latest figures from 20 May 2020 show more than 5 million people had been infected with the virus, causing more than 330,000 deaths in over 210 countries worldwide.

The large amount of information received daily relating to COVID-19 is so abundant and dynamic that medical staff, health authorities, academics and the media are not able to keep up with this new pandemic.

In order to offer a clear insight of the extensive literature available, we have conducted a comprehensive literature review of the SARS CoV-2 Virus and the Coronavirus Diseases 2019 (COVID-19).



中文翻译:

SARS-CoV-2 病毒和 2019 年冠状病毒病 (COVID-19) 的临床、分子和流行病学特征,全面的文献综述。

冠状病毒是一个广泛的病毒家族,可引起动物和人类疾病。目前的冠状病毒分类识别属于冠状病毒科的 27 个亚属 39 个物种。其中,至少已知 7 种冠状病毒会引起人类呼吸道感染。其中四种病毒可引起类似普通感冒的症状。那些感染动物的病毒可以进化并感染人类。这些病毒跳跃的最新三个例子包括 SARS CoV、MERS-CoV 和 SARS CoV-2 病毒。它们是导致严重急性呼吸综合征 (SARS)、中东呼吸综合征 (MERS) 和 2019 年最新发现的冠状病毒病 (COVID-19) 的原因。

COVID-19 是一种由 SARS-CoV-2 病毒引起的呼吸道疾病,世界卫生组织 (WHO) 于 2020 年 3 月 11 日宣布为大流行病。该疾病的迅速传播令科学界和医学界感到惊讶。2020 年 5 月 20 日的最新数据显示,已有超过 500 万人感染该病毒,导致全球 210 多个国家超过 33 万人死亡。

每天收到的有关 COVID-19 的大量信息如此丰​​富且动态,以至于医务人员、卫生当局、学术界和媒体无法跟上这一新的流行病。

为了对现有的大量文献提供清晰的了解,我们对 SARS CoV-2 病毒和 2019 年冠状病毒病 (COVID-19) 进行了全面的文献综述。

更新日期:2020-07-02
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