Semicontinuous distillation is a new separation technology for distilling multicomponent mixtures. This process was designed using design methodologies with heuristic components that evolved over 20 years. However, the fundamental philosophy of these design methodologies, which involves guessing, checking and then using a black-box optimization procedure to find the values of the design variables to meet some performance criteria, has not changed. Mainly, to address the problem of having a heuristic simulation termination criterion in the black-box optimization phase, the single shooting method for semicontinuous distillation design was proposed in this study. We envision that this is a first step in the transformation of the semicontinuous distillation design process for obtaining optimal designs. We demonstrate the application of this method using two case studies, which involve the separation of hexane, heptane and octane.

半连续蒸馏是一种用于蒸馏多组分混合物的新分离技术。此过程是使用具有20多年演变的启发式组件的设计方法进行设计的。但是，这些设计方法的基本原理并没有改变，该原理涉及猜测，检查然后使用黑盒优化程序来查找设计变量的值以满足某些性能标准。主要是为了解决黑盒优化阶段具有启发式仿真终止准则的问题，提出了一种半连续蒸馏设计的单枪法。我们设想这是为获得最佳设计而进行的半连续蒸馏设计过程的第一步。