The aim of this work is to study local changes of fractality in mouse embryonic lens. Embryos were removed from female mice that have been subjected to a diet deficient in folic acid for two and eight weeks. The local change of fractality is studied through the analysis of the Local Connected Fractal Dimension (LCFD) on binarised images of these lenses using FracLac plugin for ImageJ, after immunohistochemical analysis performed using anti-collagen IV or anti-laminin-1. The samples were analysed previously by the authors to locate under and overexpression lens zones of these proteins. The results show that there are variations of the LCFD with respect to control groups. These changes show significant positive correlations with changes in spatial patterns of both proteins expression.

这项工作的目的是研究小鼠胚胎晶状体的局部分形变化。从已经缺乏叶酸饮食两周和八周的雌性小鼠中去除胚胎。在使用抗胶原蛋白IV或抗层粘连蛋白1进行免疫组织化学分析后，通过对ImageJ使用FracLac插件对这些镜片的二值化图像进行局部连接分形维数（LCFD）的分析，研究了分形的局部变化。作者先前已对样品进行了分析，以定位这些蛋白下方和过表达的晶状体区域。结果表明，相对于对照组，LCFD存在差异。这些变化显示出与两种蛋白质表达的空间模式变化显着正相关。