A 51-year-old woman with COVID-19 infection developed coma and an impaired oculocephalic response to one side. MRI of the brain demonstrated acute multifocal demyelinating lesions, and CSF testing did not identify a direct cerebral infection. High-dose steroids followed by a course of IVIG was administered, and the patient regained consciousness over the course of several weeks. As more patients reach the weeks after initial infection with COVID-19, acute disseminated encephalomyelitis should be considered a potentially treatable cause of profound encephalopathy or multifocal neurological deficits.

中文翻译：

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与COVID-19相关的急性播散性脑脊髓炎（ADEM）。

一名患有COVID-19感染的51岁妇女发展为昏迷，一侧的眼脑反应受损。脑部MRI显示急性多灶性脱髓鞘病变，CSF检测未发现直接的脑部感染。给予大剂量的类固醇，然后进行一个IVIG疗程，患者在数周的时间内恢复了意识。随着越来越多的患者到达初次感染COVID-19后的几周，应将急性弥漫性脑脊髓炎视为严重脑病或多灶性神经功能缺损的可能可治疗原因。