Objective:

To analyze the available literature on papilledema in chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), report the first detailed pediatric case, and explore the underlying pathophysiology.

Methods:

First, we conducted a comprehensive literature review of all cases of papilledema in CIDP. Next, we reviewed each case, incorporating only those including cerebrospinal fluid analysis into the results. Finally, we present our pediatric patient.

Results:

Our literature review yielded a total of 9 adult and no pediatric cases. Cerebrospinal fluid protein and opening pressures were elevated in all cases. They were also elevated in our pediatric case.

Conclusion:

Prolonged periods of active immune-mediated inflammation is likely a cause of papilledema in adult CIDP, and possibly also in our pediatric case.

中文翻译：

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慢性炎症性脱髓鞘性多发性神经根神经病 (CIDP) 中的视乳头水肿：儿科病例和文献回顾。

客观的：

分析关于慢性炎性脱髓鞘性多发性神经根神经病 (CIDP) 视乳头水肿的现有文献，报告第一个详细的儿科病例，并探讨潜在的病理生理学。

方法：

首先，我们对 CIDP 中的所有视乳头水肿病例进行了全面的文献回顾。接下来，我们审查了每个案例，仅将包括脑脊液分析在内的案例纳入结果。最后，我们介绍我们的儿科患者。

结果：

我们的文献回顾共产生了 9 例成人病例，没有儿童病例。所有病例的脑脊液蛋白和开放压力均升高。在我们的儿科病例中，它们也升高。

结论：

长期活动性免疫介导的炎症很可能是成人 CIDP 中视乳头水肿的原因，在我们的儿科病例中也可能如此。