In the present study, we have designed a novel series of pyrazolyl-1,3,4-thiadiazole analogues by accommodating 1,3,4-thiadiazole ring at C – 4 of pyrazole ring with and without an amide linkage; 5-methyl-1,3-diphenyl-N-(5-phenyl-1,3,4-thiadiazol-2-yl)-1H-pyrazole-4-carboxamide and 2-(5-methyl-1,3-diphenyl-1H-pyrazol-4-yl)-5-phenyl-1,3,4-thiadiazole respectively. We have designed this class of heterocycles by keeping a wide audience in mind, which augment their scientific knowledge. Newly synthesized compounds were characterized by ¹H NMR, ¹³C NMR, mass, IR spectral studies. Single crystal X-ray analysis of some compounds also gave insight into the structural information.

在本研究中，我们通过在带有或不带有酰胺键的吡唑环的C–4处容纳1,3,4-噻二唑环，设计了一系列新颖的吡唑基-1,3,4-噻二唑类似物。5-甲基-1,3-二苯基-N-（5-苯基-1,3,4-噻二唑-2-基）-1 H-吡唑-4-羧酰胺和2-（5-甲基-1,3-二苯基-1H-吡唑-4-基）-5-苯基-1,3,4-噻二唑。我们在设计此类杂环时要考虑到广泛的受众，从而增加了他们的科学知识。通过¹ H NMR，¹³ C NMR，质量，IR光谱研究对新合成的化合物进行了表征。对某些化合物进行单晶X射线分析也可以洞悉结构信息。