Growing evidence supports the efficacy of various psychosocial interventions yet provides very little information about the potential harms and burdens of treatment. Lacking such information makes it difficult to make truly informed decisions about treatment options. This has proved challenging for clinical practice guideline developers, who seek to synthesize the best available research, including weighing perceived benefits, harms, and burdens of treatments, in order to formulate recommendations for clinicians, patients, and policy makers. This paper overviews the problem along with current and future implications and challenges for guideline development, including an example from the American Psychological Association's guideline on PTSD treatment. Adequate definition and reporting in published treatment trials is critical for the field to formulate careful treatment recommendations and guidelines.

中文翻译：

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危害和负担在临床实践指南中的作用：从美国心理学会指南制定中吸取的教训

越来越多的证据支持各种心理社会干预措施的有效性，但很少提供有关治疗的潜在危害和负担的信息。缺乏此类信息使得很难就治疗方案做出真正明智的决定。事实证明，这对临床实践指南制定者来说具有挑战性，他们寻求综合现有的最佳研究，包括权衡治疗的感知益处、危害和负担，以便为临床医生、患者和政策制定者制定建议。本文概述了该问题以及指南制定的当前和未来影响和挑战，包括美国心理学会关于 PTSD 治疗指南的一个例子。