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G2P[4] rotavirus outbreak in Belu, East Nusa Tenggara Province, Indonesia, 2018.
Journal of Infection and Public Health ( IF 4.7 ) Pub Date : 2020-05-29 , DOI: 10.1016/j.jiph.2020.05.002
Takako Utsumi 1 , Rury M Wahyuni 2 , Zayyin Dinana 2 , Emily Gunawan 3 , Arga S D Putra 2 , Teguh Mubawadi 4 , Soetjipto 2 , Maria I Lusida 2 , Ikuo Shoji 5
Affiliation  

Rotavirus is a major cause of acute gastroenteritis (AGE) in children worldwide. However, rotavirus outbreak has rarely been reported in Indonesia. This study aims to identify the causative agent for AGE outbreak among children in Belu, East Nusa Tenggara, Indonesia in 2018. All the samples were negative for bacteria (Salmonella, V. cholera) and Norovirus. Ten out of 11 stool samples were rotavirus-positive by immunochromatography testing. Reverse-transcription polymerase chain reaction (RT-PCR) and phylogenetic analyses revealed that rotavirus G2P[4] was the possible causative agent for the AGE outbreak, although sample size was limited. These findings suggest that the AGE outbreak was caused by rotavirus G2P[4], highlighting the importance of rotavirus surveillance.



中文翻译:

印度尼西亚东努沙登加拉省贝鲁的G2P [4]轮状病毒暴发,2018年。

轮状病毒是全世界儿童急性肠胃炎(AGE)的主要原因。但是,印度尼西亚很少有轮状病毒爆发的报道。这项研究旨在确定2018年印度尼西亚东努沙登加拉州贝鲁市儿童AGE暴发的病因。所有样本均对细菌(沙门氏菌,霍乱弧菌)和诺如病毒呈阴性。通过免疫色谱测试,在11份粪便样本中,有10份是轮状病毒阳性的。逆转录聚合酶链反应(RT-PCR)和系统发育分析表明,轮状病毒G2P [4]是AGE暴发的可能病原体,尽管样本量有限。这些发现表明AGE爆发是由轮状病毒G2P引起的[4],突出了轮状病毒监测的重要性。

更新日期:2020-05-29
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