Inorganic nanostructures have emerged as potential nanoplatforms for cancer therapy and imaging. The clinical translation of mesoporous silica nanoparticles after iron nanoparticles have led to growing interest in these nanoplatforms. The present review presents copper sulphide based nanostructures as a versatile platform for multimodal therapy and imaging of cancer. This review gives a detailed description of various synthesis methods of copper sulphide nanostructures and also discusses the various factors which can help in modulating the morphology of copper sulphide based nanostructures. The article further sheds light on the unique thermal, electronic and optical properties of these nanostructures which holds potential for biomedical applications. The role of copper sulphide nanostructures in serving as therapeutic platforms for cancer therapy has been explained along with alternative therapeutic approaches apart from chemotherapy for cancer including photothermal therapy, photodynamic therapy, radiotherapy and gene therapy. The review also inculcates the potential of copper sulphide nanoplatforms for multimodal imaging ability including MRI, radio-imaging, fluorescence imaging and photoacoustic imaging. The theranostic nanoplatform based on copper sulphide nanostructures have also been overviewed. The role of copper sulphide nanostructures in receptor targeted therapy of cancer has also been discussed in brief for better understanding of its role in targeted cancer therapy. The article gives insight about the toxicological issue associated with cooper sulphide nanoparticles and also provides regarding the recent advancements in copper sulphide nanostructures including nano-heterostructures and metal organic frameworks for future biomedical application.

无机纳米结构已经成为潜在的用于癌症治疗和成像的纳米平台。铁纳米粒子之后，介孔二氧化硅纳米粒子的临床翻译引起了人们对这些纳米平台的兴趣。本综述介绍了基于硫化铜的纳米结构作为多峰疗法和癌症成像的通用平台。这篇综述详细描述了各种硫化铜纳米结构的合成方法，并讨论了各种因素，这些因素可以帮助调节硫化铜基纳米结构的形态。这篇文章进一步阐明了这些纳米结构独特的热，电子和光学特性，这些特性为生物医学应用提供了潜力。除了用于癌症的化学疗法，包括光热疗法，光动力疗法，放射疗法和基因疗法以外，还解释了硫化铜纳米结构在用作癌症疗法的治疗平台中的作用。该评论还指出了硫化铜纳米平台在多模态成像能力方面的潜力，包括MRI，放射成像，荧光成像和光声成像。还概述了基于硫化铜纳米结构的治疗论纳米平台。为了更好地了解其在靶向癌症治疗中的作用，还简要讨论了硫化铜纳米结构在癌症受体靶向治疗中的作用。