The purpose of this study is to investigate the relation between residual SYNTAX score (rSS) and contrast-induced nephropathy (CIN) development in patients with non-ST segment elevation myocardial infarction (NSTEMI) with normal or near-to-normal left ventricular ejection fraction (LVEF) who underwent percutaneous coronary intervention (PCI). A total of 306 patients who underwent PCI with NSTEMI were included in our study. SYNTAX scores were calculated for the periods before and after PCI. Patients were divided into 2 groups as developed CIN following PCI (CIN +) and patients did not (CIN −). Fifty-four (17.6%) of patients who were included in the study developed CIN. Age (P = .001) and rSS (P = .002) were significantly higher and LVEF was lower (P = .034) in the CIN (+) group. Age (P = .031, odds ratio [OR]: 1.031, 95% CI, 1.003-1.059) and rSS (P = .04, OR: 1.036, 95% CI, 1.002-1.071) were independent predictors for CIN. In receiver operating characteristic analyses, when the cutoff value of rSS was taken as 3.5, it determined CIN with 79% sensitivity and 65% specificity. Contrast-induced nephropathy may develop more frequently in patients with increased rSS value. The rSS may be useful to follow-up these patients for CIN development.

这项研究的目的是研究左心室射血正常或接近正常的非ST段抬高型心肌梗死（NSTEMI）患者的残余SYNTAX评分（rSS）与造影剂诱发的肾病（CIN）的发展之间的关系。接受经皮冠状动脉介入治疗（PCI）的患者（LVEF）。本研究共纳入306例行NSTEMI PCI治疗的患者。计算PCI前后的SYNTAX分数。患者分为两组，分别为PCI后发生CIN（CIN +）和未发生（CIN-）。纳入研究的患者中有54（17.6％）人患有CIN。年龄（P = .001）和rSS（P = .002）明显较高而LVEF较低（P= .034）在CIN（+）组中。年龄（P = .031，优势比[OR]：1.031，95％CI，1.003-1.059）和rSS（P = .04，OR：1.036，95％CI，1.002-1.071）是CIN的独立预测因子。在接收机工作特性分析中，当rSS的截止值为3.5时，确定CIN的灵敏度为79％，特异性为65％。rSS值升高的患者中，对比剂诱发的肾病可能更频繁地发展。rSS可能有助于随访这些患者的CIN发生情况。