A growing number of studies have suggested that non‐pathologists can reliably assess the adequacy and malignancy in rapid on‐site evaluation (ROSE) smears prepared during endoscopic sampling procedures. However, no study has verified whether they can also consistently estimate the tumour burden, which is critical for the molecular profiling of lung cancer. We aimed to assess the interobserver agreement (IOA) between a pathologist, a pulmonologist (previously trained in lung and lymph node cytopathology) and a molecular pathologist for the tumour burden in ROSE smears.

中文翻译：

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病理学家、肺病学家和分子病理学家之间的观察者间协议，以估计来自超声内镜检查和引导支气管镜检查的快速现场评估涂片中的肿瘤负荷。

越来越多的研究表明，非病理学家可以可靠地评估在内窥镜取样过程中制备的快速现场评估 (ROSE) 涂片的充分性和恶性程度。然而，没有研究证实他们是否也能一致地估计肿瘤负荷，这对于肺癌的分子分析至关重要。我们旨在评估病理学家、肺病学家（之前接受过肺和淋巴结细胞病理学培训）和分子病理学家之间关于 ROSE 涂片肿瘤负荷的观察者间协议 (IOA)。